yrammuS 要概83Montian Tianprateep84NadnuddaRodthongkum 85NutthaKlinkumhom Surface Profiling Underneath Thin Transparent Layer Using Speckle Interferometry of Superluminescent Diode Based on Fourier Transform Method(Project 2016)Development of Nanocomposite Material for Toxic Heavy Metal Sensor(Project 2016)Activation of TLR3 enhance stemness and immunomodulatory properties of periodontal ligament stem cells (PDLSCs)(Project 2016)63Rep. Grant. Res., Asahi Glass Foundation (2018)Optical technique is a suitable non-destructive tool for analyzing uncoated surface. However, methods for defining the profile of coated surface are rare. In this research, 3D profile of uncoated engraved-letters surface is constructed by applied a Fast-Fourier Transform (FFT) analyzing method to speckle surface interferometry. The surface interferogram is taken from SLD Michelson Interferometer (MI). For declaring the efficiency of our method, the constructed 3D profile is compared with the one of the same uncoated surface sample, built from the interferogram taken by MI with HeNe laser. To examine the effect of materials for coating layer, Nitrocellulose and transparent hard-resin are coated on different engraved-letters surface samples. 3D profiles of coated surfaces are also produced with the same condition as in the uncoated surface sample as well.Zinc Oxide (ZnO) nanorods were prepared using zinc acetate as a precursor via thermal decomposition method and used to synthesis ZnO/graphene (ZnO/G) nanocomposites. The as prepared nanocomposite were successfully synthesized by a facile room-temperature approach using colloidal coagulation effect. Afterwards, ZnO/G nanocomposites were used for electrode surface modification in an electrochemical sensor for the simultaneous determination of cadmium (Cd2+) and lead (Pb2+). The results obtained from transmission electron microscopy and scanning electron microscopy showed that ZnO nanorods with an averate diameter of 93±21 nm were uniformly dispersed on G nanosheets. Moreover, the factor affecting on electrochemical sensitivity of this system for the simultaneous determination of Cd2+ and Pb2+ were studied and optimized using square-wave anodic stripping voltammetry. Under the optimized conditions, this system provided the detection limits (S/N=3) of 0.6 and 0.8 µgL-1 for Cd2+ and Pb2+, respectively and a linear range was found to be 10-200 µgL-1. Furthermore, this system provided the satisfied results for determination of Cd2+ and Pb2+ in wastewater samples compared with a standard inductively coupled plasma-optical emission spectroscopy.Periodontal ligament stem cells (PDLSCs) have been served as a cell reservoir for tissue regeneration during adulthood. However, the challenging steps are to maintain the stem cell properties and to improve the regeneration capacity of PDLSCs during culture. Toll-like receptor 3 (TLR3) signaling has been shown to enhance therapeutic potential in mesenchymal stem cells by induce the secretion of trophic factors. However, the role of TLR3 in PDLSCs is still unknown. The aims of this study was to investigate the responses of PDLSCs after TLR3 engagement using TLR3 agonist, poly(I:C). The result indicated that stimulation of TLR3 significantly enhanced stem cell (REX-1 and SOX2) as well as immunomodulatory (IFNg and IDO) expressions. Interestingly, inhibition of NF-κB signaling decreased TLR3-activated IFNg, but increased
元のページ ../index.html#67