旭硝子財団助成研究成果報告2023

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123Melia FAMIOLA124Muhammad IQBALFaizal Immaddudin Wira ROHMAT125Turning waste into values with community based approach(Project 2022)Development of Surface-Plasmon Resonance (SPR) Biosensor Based on 2-Dimensional Transition Metal Dichalcogenide (MoS2) Nanosheets for the Detection of Cholesterol(Project 2022)Development of Majalaya Watershed’s Future Extreme Flows Projection using Remote Sensing and Machine Learning Methods(Project 2022)旭硝子財団　助成研究成果報告（2023）84expression of enteric pathogens in stunted were higher than in normal children and negatively correlated to the level of IGF-1. These findings showed that proper dietary intake and adequate sanitary and hygiene were important to maintain gut microbiota function in supporting the linear growth in children.This research aims to develop a system to turn waste into valuable things through products and innovations that help an urban community create its circular model. It starts with social innovation in a community to want to see new opportunities from waste. Several products and innovations have been developed, making waste into valuable products while creating an integrated and circular system in society. The digital model of this research was raised from this social innovation and waste-based products. Hopefully, this will connect urban communities with sustainability more quickly, effectively, and inclusively. The digital system developed in this research does not view waste as a single issue needed to be solved. The waste management in this study is connected with other urban problems, namely food insecurity and urban economic disparities, which are characteristic of urban problems in the majority of cities in developing countries.By integrating these three issues, the value of waste will be higher in the public’s perception.This study presents the modification of a surface plasmon resonance (SPR) chip with MoS2 for the detection of cholesterol. MoS2 was synthesized using hydrothermal methods with varying pH and trisodium citrate (Na3Ct) concentrations, which were anticipated to affect the shape and size of the particles. The addition of Na3Ct as a reducing agent resulted in a reduction in the particle size of MoS2. These MoS2 variations with different sizes were subsequently employed as modifiers on Au chips to examine the influence of particle size on detection performance. In general, the Au/MoS2 biosensor chip exhibited a detection response for cholesterol that was twice as high as that of the bare Au chip. It was observed that the deposition of MoS2 with larger particle sizes yielded higher detection responses, increased sensitivity, and lower detection limits (LOD). These findings are associated with the compatibility between the particle size of the material and the size of the target and bioreceptor. Among the different fabricated chip, Au/MoS2-1 was identified as the most effective sensor chip due to its largest particles size of ~900 nm. This chip demonstrating excellent sensitivity and an LOD of 0.10054 RU/mM and 8.31 mM (S/N = 3), respectively. This study provides compelling evidence that MoS2 can significantly enhance the performance of SPR biosensors. Furthermore, it elucidates the notable impact of material particle size on the improvement of detection performance in biosensors.With an average of six floods yearly, Majalaya Subdistrict is one of Greater Bandung’s most valued economic regions. In the area, people only have a little time to take preventative measures to lessen the loss because